Gene Review:
pitx - paired superclass homeobox transcription...
Ciona intestinalis
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High impact information on pitx
- Accordingly, a prominent conserved feature of pitx genes in chordates is their early expression in the anterior neural boundary (ANB) and oral ectoderm, also known as the stomodaeum [1].
- Pituitary homeobox (pitx) genes have been identified in vertebrates as critical molecular determinants of various craniofacial ontogenetic processes including pituitary organogenesis [1].
Analytical, diagnostic and therapeutic context of pitx
- We next combined phylogenetic footprinting, transient transgenesis, and confocal imaging methods to study the Ci-pitx cis-regulatory system, with special emphasis on the regulation of isoform-specific ANB/stomodaeal expression [1].
References
- A modular cis-regulatory system controls isoform-specific pitx expression in ascidian stomodaeum. Christiaen, L., Bourrat, F., Joly, J.S. Dev. Biol. (2005) [Pubmed]
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