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Gene Review

dom  -  domino

Drosophila melanogaster

Synonyms: 27/4, CG9696, DOM, Dmel\CG9696, Dom, ...
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High impact information on dom

  • The Domino proteins are present in large complexes in embryo extracts, and one isoform binds to a number of discrete sites on larval polytene chromosomes [1].
  • These features are shared with three other components of TIP60 complexes, namely Enhancer of Polycomb, Domino, and dMRG15 [2].
  • The iswi mutant germline stem cells are lost rapidly because of defects in responding to bone morphogenetic protein niche signals and in repressing differentiation, whereas the dom mutant somatic stem cells are lost because of defective self-renewal [3].


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