Gene Review:
Pc - Polycomb
Drosophila melanogaster
Synonyms:
CG32443, CG7618, DmPc, Dmel\CG32443, PC, ...
- The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6). Boccuni, P., MacGrogan, D., Scandura, J.M., Nimer, S.D. J. Biol. Chem. (2003)
- Transvection and silencing of the Scr homeotic gene of Drosophila melanogaster. Southworth, J.W., Kennison, J.A. Genetics (2002)
- The Drosophila trithorax proteins contain a novel variant of the nuclear receptor type DNA binding domain and an ancient conserved motif found in other chromosomal proteins. Stassen, M.J., Bailey, D., Nelson, S., Chinwalla, V., Harte, P.J. Mech. Dev. (1995)
- Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster. Tolhuis, B., de Wit, E., Muijrers, I., Teunissen, H., Talhout, W., van Steensel, B., van Lohuizen, M. Nat. Genet. (2006)
- Genome-wide analysis of Polycomb targets in Drosophila melanogaster. Schwartz, Y.B., Kahn, T.G., Nix, D.A., Li, X.Y., Bourgon, R., Biggin, M., Pirrotta, V. Nat. Genet. (2006)
- RNAi components are required for nuclear clustering of Polycomb group response elements. Grimaud, C., Bantignies, F., Pal-Bhadra, M., Ghana, P., Bhadra, U., Cavalli, G. Cell (2006)
- Mapping Polycomb-repressed domains in the bithorax complex using in vivo formaldehyde cross-linked chromatin. Orlando, V., Paro, R. Cell (1993)
- Polycomb group-dependent Cyclin A repression in Drosophila. Martinez, A.M., Colomb, S., Déjardin, J., Bantignies, F., Cavalli, G. Genes Dev. (2006)
- The Drosophila polycomb group protein Psc contacts ph and Pc through specific conserved domains. Kyba, M., Brock, H.W. Mol. Cell. Biol. (1998)
- Elements of the Drosophila bithorax complex that mediate repression by Polycomb group products. Simon, J., Chiang, A., Bender, W., Shimell, M.J., O'Connor, M. Dev. Biol. (1993)
- Phenotypic consequences and genetic interactions of a null mutation in the Drosophila Posterior Sex Combs gene. Adler, P.N., Martin, E.C., Charlton, J., Jones, K. Dev. Genet. (1991)
- Stage-specific expression of polycomb group genes in human bone marrow cells. Lessard, J., Baban, S., Sauvageau, G. Blood (1998)
- Mutations in some Polycomb group genes of Drosophila interfere with regulation of segmentation genes. McKeon, J., Slade, E., Sinclair, D.A., Cheng, N., Couling, M., Brock, H.W. Mol. Gen. Genet. (1994)
- Effects of Polycomb group mutations on the expression of Ultrabithorax in the Drosophila visceral mesoderm. Choi, S.H., Oh, C.T., Kim, S.H., Kim, Y.T., Jeon, S.H. Mol. Cells (2000)
- Direct interaction of the Polycomb protein with Antennapedia regulatory sequences in polytene chromosomes of Drosophila melanogaster. Zink, B., Engström, Y., Gehring, W.J., Paro, R. EMBO J. (1991)
- Functional reconstruction of trans regulation of the Ultrabithorax promoter by the products of two antagonistic genes, trithorax and Polycomb. Chang, Y.L., King, B.O., O'Connor, M., Mazo, A., Huang, D.H. Mol. Cell. Biol. (1995)
- Transient requirements of YY1 expression for PcG transcriptional repression and phenotypic rescue. Srinivasan, L., Pan, X., Atchison, M.L. J. Cell. Biochem. (2005)
- Mapping functional domains of the polycomb protein of Drosophila melanogaster. Franke, A., Messmer, S., Paro, R. Chromosome Res. (1995)
- pipsqueak encodes a factor essential for sequence-specific targeting of a polycomb group protein complex. Huang, D.H., Chang, Y.L., Yang, C.C., Pan, I.C., King, B. Mol. Cell. Biol. (2002)
- Double chromodomains cooperate to recognize the methylated histone H3 tail. Flanagan, J.F., Mi, L.Z., Chruszcz, M., Cymborowski, M., Clines, K.L., Kim, Y., Minor, W., Rastinejad, F., Khorasanizadeh, S. Nature (2005)
- Probes of chromatin accessibility in the Drosophila bithorax complex respond differently to Polycomb-mediated repression. McCall, K., Bender, W. EMBO J. (1996)
- A Drosophila ESC-E(Z) protein complex is distinct from other polycomb group complexes and contains covalently modified ESC. Ng, J., Hart, C.M., Morgan, K., Simon, J.A. Mol. Cell. Biol. (2000)
- Pleiohomeotic can link polycomb to DNA and mediate transcriptional repression. Mohd-Sarip, A., Venturini, F., Chalkley, G.E., Verrijzer, C.P. Mol. Cell. Biol. (2002)
- Trl-GAGA directly interacts with lola like and both are part of the repressive complex of Polycomb group of genes. Mishra, K., Chopra, V.S., Srinivasan, A., Mishra, R.K. Mech. Dev. (2003)
- Transcription factor YY1 functions as a PcG protein in vivo. Atchison, L., Ghias, A., Wilkinson, F., Bonini, N., Atchison, M.L. EMBO J. (2003)
- Tissue specificity of hedgehog repression by the Polycomb group during Drosophila melanogaster development. Chanas, G., Maschat, F. Mech. Dev. (2005)
- The Additional sex combs gene of Drosophila is required for activation and repression of homeotic loci, and interacts specifically with Polycomb and super sex combs. Milne, T.A., Sinclair, D.A., Brock, H.W. Mol. Gen. Genet. (1999)
- Establishment of Polycomb silencing requires a transient interaction between PC and ESC. Poux, S., Melfi, R., Pirrotta, V. Genes Dev. (2001)
- The Drosophila Polycomb group gene pleiohomeotic encodes a DNA binding protein with homology to the transcription factor YY1. Brown, J.L., Mucci, D., Whiteley, M., Dirksen, M.L., Kassis, J.A. Mol. Cell (1998)
- Binding of trithorax and Polycomb proteins to the bithorax complex: dynamic changes during early Drosophila embryogenesis. Orlando, V., Jane, E.P., Chinwalla, V., Harte, P.J., Paro, R. EMBO J. (1998)
- Dosage-dependent modifiers of polycomb and antennapedia mutations in Drosophila. Kennison, J.A., Tamkun, J.W. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Transcriptional repression by Drosophila and mammalian Polycomb group proteins in transfected mammalian cells. Bunker, C.A., Kingston, R.E. Mol. Cell. Biol. (1994)
- Trithorax- and Polycomb-group response elements within an Ultrabithorax transcription maintenance unit consist of closely situated but separable sequences. Tillib, S., Petruk, S., Sedkov, Y., Kuzin, A., Fujioka, M., Goto, T., Mazo, A. Mol. Cell. Biol. (1999)