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Gene Review:

dmbx - Dmbx protein

Ciona intestinalis

Takahashi, T. et al., Takahashi, T.

Takahashi,

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High impact information on Dmbx

Amphioxus and ascidian Dmbx homeobox genes give clues to the vertebrate origins of midbrain development [1].
We report the cloning, genomic structure, phylogeny and embryonic expression of Dmbx genes from amphioxus and from Ciona, representing the two most closely related lineages to the vertebrates [1].
Our analyses show that Dmbx genes form a distinct, ancient, homeobox gene family, with highly conserved sequence and genomic organisation, albeit more divergent in Ciona [1].
The evolutionary origins of vertebrate midbrain and MHB: insights from mouse, amphioxus and ascidian Dmbx homeobox genes [2].

References

Amphioxus and ascidian Dmbx homeobox genes give clues to the vertebrate origins of midbrain development. Takahashi, T., Holland, P.W. Development (2004) [Pubmed]
The evolutionary origins of vertebrate midbrain and MHB: insights from mouse, amphioxus and ascidian Dmbx homeobox genes. Takahashi, T. Brain Res. Bull. (2005) [Pubmed]

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