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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Ero1l  -  ERO1-like (S. cerevisiae)

Mus musculus

Synonyms: ERO1-L, ERO1-L-alpha, ERO1-like protein alpha, Endoplasmic reticulum oxidoreductin-1-like protein, Oxidoreductin-1-L-alpha
 
 
 
 
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High impact information on Ero1l

  • These results strongly suggest that ERO1-L is involved in oxidative ER protein folding in mammalian cells [1].
  • ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum [1].
  • ERO1-L is able to complement several phenotypic traits of the yeast thermosensitive mutant ero1-1, including temperature and dithiothreitol sensitivity, and intrachain disulfide bond formation in carboxypeptidase Y [1].
  • In isolated microsomes, ERO1-L behaves as a type II integral membrane protein [1].

References

  1. ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum. Cabibbo, A., Pagani, M., Fabbri, M., Rocchi, M., Farmery, M.R., Bulleid, N.J., Sitia, R. J. Biol. Chem. (2000) [Pubmed]
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