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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

CCR7  -  chemokine (C-C motif) receptor 7

Bos taurus

 
 
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High impact information on CCR7

  • We describe full-length cDNA sequences of bovine chemokine receptors CCR5, CCR7, CXCR3 and CXCR5 and transcript expression by WC1(+)gammadelta T cells, a unique cell population with proinflammatory characteristics that comprises a large proportion of mononuclear cells in young ruminants [1].
  • CC chemokine receptor 7 (CCR7) is selectively expressed on mature dendritic cells (DC) [2].

References

  1. Molecular cloning of bovine chemokine receptors and expression by WC1+ gammadelta T cells. Blumerman, S.L., Wang, F., Herzig, C.T., Baldwin, C.L. Dev. Comp. Immunol. (2007) [Pubmed]
  2. CCR7 ligand-enhanced phagocytosis of various antigens in mature dendritic cells-time course and antigen distribution different from phagocytosis in immature dendritic cells. Kikuchi, K., Yanagawa, Y., Onoé, K. Microbiol. Immunol. (2005) [Pubmed]
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