Gene Review:
Ccr7 - chemokine (C-C motif) receptor 7
Mus musculus
Synonyms:
C-C CKR-7, C-C chemokine receptor type 7, CC-CKR-7, CCR-7, CD197, ...
Junt,
Scandella,
Förster,
Krebs,
Krautwald,
Lipp,
Hengartner,
Ludewig,
Höpken,
Droese,
Li,
Joergensen,
Breitfeld,
Zerwes,
Lipp,
Okada,
Masunaga,
Okada,
Iiyama,
Mori,
Tsuda,
Matsubara,
Mizuguchi,
Hayakawa,
Fujita,
Yamamoto,
Stein,
Soriano,
M'rini,
Nombela-Arrieta,
de Buitrago,
Rodríguez-Frade,
Mellado,
Girard,
Martínez-A,
- Enhanced allergen-induced airway inflammation in paucity of lymph node T cell (plt) mutant mice. Grinnan, D., Sung, S.S., Dougherty, J.A., Knowles, A.R., Allen, M.B., Rose, C.E., Nakano, H., Gunn, M.D., Fu, S.M., Rose, C.E. J. Allergy Clin. Immunol. (2006)
- Defective CCR7 expression on dendritic cells contributes to the development of visceral leishmaniasis. Ato, M., Stäger, S., Engwerda, C.R., Kaye, P.M. Nat. Immunol. (2002)
- Differential requirements for the chemokine receptor CCR7 in T cell activation during Listeria monocytogenes infection. Kursar, M., Höpken, U.E., Koch, M., Köhler, A., Lipp, M., Kaufmann, S.H., Mittrücker, H.W. J. Exp. Med. (2005)
- Impact of CCR7 on priming and distribution of antiviral effector and memory CTL. Junt, T., Scandella, E., Förster, R., Krebs, P., Krautwald, S., Lipp, M., Hengartner, H., Ludewig, B. J. Immunol. (2004)
- The role of CCR7 in TH1 and TH2 cell localization and delivery of B cell help in vivo. Randolph, D.A., Huang, G., Carruthers, C.J., Bromley, L.E., Chaplin, D.D. Science (1999)
- CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance. Kurobe, H., Liu, C., Ueno, T., Saito, F., Ohigashi, I., Seach, N., Arakaki, R., Hayashi, Y., Kitagawa, T., Lipp, M., Boyd, R.L., Takahama, Y. Immunity (2006)
- Requirements for follicular exclusion and competitive elimination of autoantigen-binding B cells. Ekland, E.H., Forster, R., Lipp, M., Cyster, J.G. J. Immunol. (2004)
- CC chemokine receptor 7-dependent and -independent pathways for lymphocyte homing: modulation by FTY720. Henning, G., Ohl, L., Junt, T., Reiterer, P., Brinkmann, V., Nakano, H., Hohenberger, W., Lipp, M., Förster, R. J. Exp. Med. (2001)
- Cooperating mechanisms of CXCR5 and CCR7 in development and organization of secondary lymphoid organs. Ohl, L., Henning, G., Krautwald, S., Lipp, M., Hardtke, S., Bernhardt, G., Pabst, O., Förster, R. J. Exp. Med. (2003)
- CCR7 ligands induce rapid endocytosis in mature dendritic cells with concomitant up-regulation of Cdc42 and Rac activities. Yanagawa, Y., Onoé, K. Blood (2003)
- Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming. Martín-Fontecha, A., Thomsen, L.L., Brett, S., Gerard, C., Lipp, M., Lanzavecchia, A., Sallusto, F. Nat. Immunol. (2004)
- CXCL12 mediates CCR7-independent homing of central memory cells, but not naive T cells, in peripheral lymph nodes. Scimone, M.L., Felbinger, T.W., Mazo, I.B., Stein, J.V., Von Andrian, U.H., Weninger, W. J. Exp. Med. (2004)
- Chemokine requirements for B cell entry to lymph nodes and Peyer's patches. Okada, T., Ngo, V.N., Ekland, E.H., Förster, R., Lipp, M., Littman, D.R., Cyster, J.G. J. Exp. Med. (2002)
- CCR7-mediated physiological lymphocyte homing involves activation of a tyrosine kinase pathway. Stein, J.V., Soriano, S.F., M'rini, C., Nombela-Arrieta, C., de Buitrago, G.G., Rodríguez-Frade, J.M., Mellado, M., Girard, J.P., Martínez-A, C. Blood (2003)
- FTY720-enhanced T cell homing is dependent on CCR2, CCR5, CCR7, and CXCR4: evidence for distinct chemokine compartments. Yopp, A.C., Fu, S., Honig, S.M., Randolph, G.J., Ding, Y., Krieger, N.R., Bromberg, J.S. J. Immunol. (2004)
- Induction of CCR7 expression in thymocytes requires both ERK signal and Ca(2+) signal. Adachi, S., Kuwata, T., Miyaike, M., Iwata, M. Biochem. Biophys. Res. Commun. (2001)
- Regulation of dendritic cell migration and adaptive immune response by leukotriene B4 receptors: a role for LTB4 in up-regulation of CCR7 expression and function. Del Prete, A., Shao, W.H., Mitola, S., Santoro, G., Sozzani, S., Haribabu, B. Blood (2007)
- Gene transduction efficiency and maturation status in mouse bone marrow-derived dendritic cells infected with conventional or RGD fiber-mutant adenovirus vectors. Okada, N., Masunaga, Y., Okada, Y., Iiyama, S., Mori, N., Tsuda, T., Matsubara, A., Mizuguchi, H., Hayakawa, T., Fujita, T., Yamamoto, A. Cancer Gene Ther. (2003)
- Population analysis of CD4+ T cell chemokine receptor transcript expression during in vivo type-1 (mycobacterial) and type-2 (schistosomal) immune responses. Chiu, B.C., Shang, X.Z., Stolberg, V.R., Komuniecki, E., Chensue, S.W. J. Leukoc. Biol. (2002)
- The subpopulation of CD4+CD25+ splenocytes that delays adoptive transfer of diabetes expresses L-selectin and high levels of CCR7. Szanya, V., Ermann, J., Taylor, C., Holness, C., Fathman, C.G. J. Immunol. (2002)
- Loss of Dendritic Cell Migration and Impaired Resistance to Leishmania donovani Infection in Mice Deficient in CCL19 and CCL21. Ato, M., Maroof, A., Zubairi, S., Nakano, H., Kakiuchi, T., Kaye, P.M. J. Immunol. (2006)
- Regulation of T-lymphocyte trafficking by ICAM-1, MAdCAM-1, and CCR7 in microcirculation of appendicular and intestinal lymphoid tissues. Nagamatsu, H., Tsuzuki, Y., Matsuzaki, K., Miyazaki, J., Okada, Y., Hokari, R., Kawaguchi, A., Nagao, S., Itoh, K., Miura, S. Microcirculation (New York, N.Y. : 1994) (2004)
- CC chemokine receptor-7 on dendritic cells is induced after interaction with apoptotic tumor cells: critical role in migration from the tumor site to draining lymph nodes. Hirao, M., Onai, N., Hiroishi, K., Watkins, S.C., Matsushima, K., Robbins, P.D., Lotze, M.T., Tahara, H. Cancer Res. (2000)
- Mammalian and viral IL-10 enhance C-C chemokine receptor 5 but down-regulate C-C chemokine receptor 7 expression by myeloid dendritic cells: impact on chemotactic responses and in vivo homing ability. Takayama, T., Morelli, A.E., Onai, N., Hirao, M., Matsushima, K., Tahara, H., Thomson, A.W. J. Immunol. (2001)
- Prolongation of allograft survival in ccr7-deficient mice. Beckmann, J.H., Yan, S., Lührs, H., Heid, B., Skubich, S., Förster, R., Hoffmann, M.W. Transplantation (2004)
- The chemokine receptor CCR7 controls lymph node-dependent cytotoxic T cell priming in alloimmune responses. Höpken, U.E., Droese, J., Li, J.P., Joergensen, J., Breitfeld, D., Zerwes, H.G., Lipp, M. Eur. J. Immunol. (2004)