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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

IER5  -  immediate early response 5

Homo sapiens

Synonyms: Immediate early response gene 5 protein, PP4583, SBBI48
 
 
 
 
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High impact information on IER5

  • The sequence of the promoter region of Ier5 was determined and examined for transcription factor binding sites thought to mediate serum and growth factor response [1].
  • Ier5, a novel member of the slow-kinetics immediate-early genes [1].
  • The predicted nuclear localization of Ier5, coupled with the potential for rapid regulation by phosphorylation and/or degradation, suggests that Ier5 may play an important role in mediating the cellular response to mitogenic signals [1].

References

  1. Ier5, a novel member of the slow-kinetics immediate-early genes. Williams, M., Lyu, M.S., Yang, Y.L., Lin, E.P., Dunbrack, R., Birren, B., Cunningham, J., Hunter, K. Genomics (1999) [Pubmed]
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