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NIP7  -  NIP7, nucleolar pre-rRNA processing protein

Homo sapiens

Synonyms: 60S ribosome subunit biogenesis protein NIP7 homolog, CGI-37, FLJ10296, HSPC031, HSPC180, ...
 
 
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High impact information on NIP7

  • Nop132 also interacts with human Nip7 and is colocalized with RRAG A, RRAG C, and Nip7 [1].
  • The protein KD93, which is encoded by the open reading frame HSPC031, is a NIP7 homologue and belongs to the UPF0113 family [2].
  • The crystal structure of a novel hypothetical protein, KD93, expressed in human hematopoietic stem/progenitor cells, was determined at 1.9A resolution using the multiple-wavelength anomalous dispersion (MAD) method [2].
  • Structure-based homology analysis with DALI revealed that the C domain of KD93 matches the PUA domain of some RNA modification enzymes, especially that of archaeosine tRNA-ribosyltransferase (ArcTGT), which suggests that its possible molecular function is related to RNA binding [2].

References

  1. A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D. Sekiguchi, T., Todaka, Y., Wang, Y., Hirose, E., Nakashima, N., Nishimoto, T. J. Biol. Chem. (2004) [Pubmed]
  2. Crystal structure of KD93, a novel protein expressed in human hematopoietic stem/progenitor cells. Liu, J.F., Wang, X.Q., Wang, Z.X., Chen, J.R., Jiang, T., An, X.M., Chang, W.R., Liang, D.C. J. Struct. Biol. (2004) [Pubmed]
 
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