Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

NOL7 - nucleolar protein 7, 27kDa

Homo sapiens

Synonyms: C6orf90, NOP27, Nucleolar protein 7, Nucleolar protein of 27 kDa, PQBP3, ...

Hasina, R. et al.

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High impact information on NOL7

Transfection of NOL7 into cervical carcinoma cells inhibited their growth in mouse xenografts, confirming its in vivo tumor suppressor activity [1].
Fluorescence in situ hybridization analysis demonstrated an allelic loss of an NOL7 in cultured tumor cells and human tumor samples [1].
Here we report the cloning NOL7, its mapping to chromosome band 6p23, and localization of the protein to the nucleolus [1].
These data suggest that NOL7 may function as a TSG in part by modulating the expression of the angiogenic phenotype [1].

References

NOL7 is a nucleolar candidate tumor suppressor gene in cervical cancer that modulates the angiogenic phenotype. Hasina, R., Pontier, A.L., Fekete, M.J., Martin, L.E., Qi, X.M., Brigaudeau, C., Pramanik, R., Cline, E.I., Coignet, L.J., Lingen, M.W. Oncogene (2006) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

NOL7	Bos taurus
NOL7	Canis lupus familiaris
nol7	Danio rerio
NOL7	Gallus gallus
NOL7	Macaca mulatta
Nol7	Mus musculus
NOL7	Pan troglodytes
Nol7	Rattus norvegicus
LOC100489073	Xenopus (Silurana) tropicalis

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