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Gene Review

GPR173  -  G protein-coupled receptor 173

Homo sapiens

Synonyms: SREB3, Super conserved receptor expressed in brain 3
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High impact information on GPR173

  • Further, the anatomical expression of SREB1 and SREB3 overlapped with that of SREB2 in the adult monkey brain [1].
  • Amino acid sequence identity between human and rat orthologues is 97% for SREB1 and 99% for SREB3, while the SREB2 sequence is surprisingly completely identical between the species [2].

Biological context of GPR173


  1. A conserved mRNA expression profile of SREB2 (GPR85) in adult human, monkey, and rat forebrain. Matsumoto, M., Beltaifa, S., Weickert, C.S., Herman, M.M., Hyde, T.M., Saunders, R.C., Lipska, B.K., Weinberger, D.R., Kleinman, J.E. Brain Res. Mol. Brain Res. (2005) [Pubmed]
  2. An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system. Matsumoto, M., Saito, T., Takasaki, J., Kamohara, M., Sugimoto, T., Kobayashi, M., Tadokoro, M., Matsumoto, S., Ohishi, T., Furuichi, K. Biochem. Biophys. Res. Commun. (2000) [Pubmed]
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