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Gene Review

Dfna5  -  deafness, autosomal dominant 5 (human)

Mus musculus

Synonyms: 2310037D07Rik, 4932441K13Rik, Dfna5h, EG14210, Fin15, ...
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Disease relevance of Dfna5h


High impact information on Dfna5h

  • Morphological studies demonstrated significant differences in the number of fourth row outer hair cells between Dfna5-/- mice and their wild-type littermates [1].
  • In contrast to the results obtained in Dfna5-/- zebrafish, we did not observe different UDP-glucose dehydrogenase and hyaluronic acid levels in Dfna5-/- mice when compared to Dfna5+/+ mice [1].


  1. Mice lacking Dfna5 show a diverging number of cochlear fourth row outer hair cells. Van Laer, L., Pfister, M., Thys, S., Vrijens, K., Mueller, M., Umans, L., Serneels, L., Van Nassauw, L., Kooy, F., Smith, R.J., Timmermans, J.P., Van Leuven, F., Van Camp, G. Neurobiol. Dis. (2005) [Pubmed]
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