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Gene Review

ANKRD49  -  ankyrin repeat domain 49

Homo sapiens

Synonyms: Ankyrin repeat domain-containing protein 49, FGIF, FLJ20189, Fetal globin-inducing factor, GBIF
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Disease relevance of ANKRD49

  • Our study demonstrates that suppression of FGIF production by circulating PBML occurs in animals with lung fibrosis and suggests that mechanisms other than impairment of IL-1 production may be responsible for the suppressive effect of asbestos on the production of such fibroblast regulatory lymphokine [1].


  1. Immunoregulation of lung fibroblast growth: alteration in asbestos-induced pulmonary fibrosis. Lemaire, I., Dubois, C., Grondin, C., Gingras, D. Clin. Exp. Immunol. (1986) [Pubmed]
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