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Gene Review

HCFC1R1  -  host cell factor C1 regulator 1 (XPO1...

Homo sapiens

Synonyms: FLJ20568, HCF-1 beta-propeller-interacting protein, HPIP, Host cell factor C1 regulator 1
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High impact information on HCFC1R1

  • These data suggest that HPIP regulates HCF-1 activity by modulating its subcellular localization [1].
  • These are [Zn(3)(p-BDC)(4)].2HPIP, 2 (HPIP is partly protonated piperazine), and [Zn(3)(p-BDC)(3)(H(2)BDC)].(C(6)H(15)NO).H(2)O.3DMF, 3 (C(6)H(15)NO is triethylamine N-oxide) [2].

Biological context of HCFC1R1


Other interactions of HCFC1R1

  • Furthermore, HPIP-mediated export may provide the pool of cytoplasmic HCF-1 required for import of virion-derived VP16 into the nucleus [1].


  1. Interaction of HCF-1 with a cellular nuclear export factor. Mahajan, S.S., Little, M.M., Vazquez, R., Wilson, A.C. J. Biol. Chem. (2002) [Pubmed]
  2. Construction of 3D Layer-Pillared Homoligand Coordination Polymers from a 2D Layered Precursor. Sun, J., Zhou, Y., Fang, Q., Chen, Z., Weng, L., Zhu, G., Qiu, S., Zhao, D. Inorganic chemistry. (2006) [Pubmed]
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