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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

KBTBD4  -  kelch repeat and BTB (POZ) domain...

Homo sapiens

Synonyms: BKLHD4, BTB and kelch domain-containing protein 4, FLJ10450, HSPC252, Kelch repeat and BTB domain-containing protein 4
 
 
 
 
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High impact information on KBTBD4

  • 2. Four of these ESTs/genes (FLJ23598, FLJ10450, KIAA1580, SYT13) mapped to the minimal tumor suppressor region of human 11p11.2, the smallest region conferring suppression of tumorigenicity in the MCH cell lines [1].
  • Three ESTs/genes (FLJ23598, FLJ10450, KIAA1580) proved to be less than ideal candidates, based upon their loss from suppressed MCH cell lines (DNA deletion), and/or their retention and expression in a non-suppressed MCH cell line [1].

References

  1. Identification of candidate liver tumor suppressor genes from human 11p11.2 by transcription mapping of microcell hybrid cell lines. Jahn, J.E., Ricketts, S.L., Coleman, W.B. Int. J. Oncol. (2003) [Pubmed]
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