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Gene Review

SYT13  -  synaptotagmin XIII

Homo sapiens

Synonyms: KIAA1427, Synaptotagmin XIII, Synaptotagmin-13, SytXIII
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High impact information on SYT13

  • Since Syt XIII is expressed in various tissues outside the brain, Syt XIII may be involved in constitutive vesicle transport [1].
  • Because of these substitutions, the Syt XIII C2 domains did not show Ca2+-dependent phospholipid-binding activity, and Syt XIII is thus classified as a Ca2+ -independent isoform [1].
  • In contrast, SYT13 is present in the DNA from all suppressed MCH cell lines (n=10), and is deleted in a non-suppressed MCH cell line [2].
  • Furthermore, SYT13 mRNA is expressed in 100% of suppressed cell lines, and is not expressed in the non-suppressed MCH cell line or in MCH-derived tumor cell lines (n=6) [2].


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