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Gene Review

Pgam2  -  phosphoglycerate mutase 2

Mus musculus

Synonyms: BPG-dependent PGAM 2, Muscle-specific phosphoglycerate mutase, PGAM-M, Phosphoglycerate mutase 2, Phosphoglycerate mutase isozyme M
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High impact information on Pgam2

  • Developmental activation of phosphoglycerate mutase-2 in the testis of the mouse [1].
  • The partial genomic sequence of Pgam2 was determined, which showed that mouse Pgam2 consisted at least three exons and two introns [2].

Anatomical context of Pgam2

  • Pgam1 was expressed as a 2.1-kb transcript highly in brain and kidney and moderately in liver, thyroid, stomach and heart, whereas Pgam2 was expressed as a 1.0-kb transcript highly in muscle, testis and moderately in heart and lung, but was not detectable in the other six tissues examined [2].


  1. Developmental activation of phosphoglycerate mutase-2 in the testis of the mouse. Fundele, R., Winking, H., Illmensee, K., Jägerbauer, E.M. Dev. Biol. (1987) [Pubmed]
  2. Mouse phosphoglycerate mutase M and B isozymes: cDNA cloning, enzyme activity assay and mapping. Zhang, J., Yu, L., Fu, Q., Gao, J., Xie, Y., Chen, J., Zhang, P., Liu, Q., Zhao, S. Gene (2001) [Pubmed]
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