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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

CRTAM  -  cytotoxic and regulatory T cell molecule

Homo sapiens

Synonyms: CD355, Class-I MHC-restricted T-cell-associated molecule, Cytotoxic and regulatory T-cell molecule
 
 
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High impact information on CRTAM

  • We here review current knowledge on these receptors, CD226, CD96 and CRTAM, and their role in tumor immunosurveillance [1].
  • In addition, the human region 3q13 and its paralogs, harbour genes remotely related to the nectin family that can be detected in Protostomes (human CRTAM and CD80-86 related to Drosophila Beat) [2].

References

  1. The role of NK cell recognition of nectin and nectin-like proteins in tumor immunosurveillance. Fuchs, A., Colonna, M. Semin. Cancer Biol. (2006) [Pubmed]
  2. Innate immunity in early chordates and the appearance of adaptive immunity. Du Pasquier, L. C. R. Biol. (2004) [Pubmed]
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