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Gene Review:

VTRNA1-3 - vault RNA 1-3

Homo sapiens

Synonyms: HVG3, VAULTRC3, VR3, hvg-3, vtRNA1-3

Sacchi, C.T. et al., Iliescu, R. et al., Park, J.K. et al., van Zon, A. et al.

Sacchi, de Lemos, Whitney, Melles, Solari, Frasch, Mayer,

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Disease relevance of VAULTRC3

The effect of violamycin BI (VBI) was investigated in different cell substrates, infected or not with herpes simplex virus type 1 (HSV-1), strains VR3 and Rapp-1 [1].

High impact information on VAULTRC3

Interestingly, an increased amount of hvg3 was bound to vaults isolated from multidrug-resistant cell lines [2].
The telomere length of VR3 decreased compared to that of normal RPE cells and the decrease continued during subculture [3].
The results of DNA probes 21U (VR1-A) and 615U (VR3-B) used against 72 N. meningitidis strains confirm that VR1 type A and VR3 type B encode epitopes for serotype-defined MAbs 19 and 10, respectively [4].

References

The effect of violamycin BI on different biological systems. Note I. The action of violamycin BI on cell cultures infected or not with herpes simplex virus type 1. Iliescu, R., Muţiu, A., Sahnazarov, N., Mihalache, O., Repanovici, R., Löber, G., Popa, L.M. Virologie. (1981) [Pubmed]
Multiple human vault RNAs. Expression and association with the vault complex. van Zon, A., Mossink, M.H., Schoester, M., Scheffer, G.L., Scheper, R.J., Sonneveld, P., Wiemer, E.A. J. Biol. Chem. (2001) [Pubmed]
The effect of telomerase expression on the escape from M2 crisis in virus-transformed human retinal pigment epithelial cells. Park, J.K., Kim, B.H., Han, Y.S., Park, I.K. Exp. Mol. Med. (2002) [Pubmed]
The use of oligonucleotide probes for meningococcal serotype characterization. Sacchi, C.T., de Lemos, A.P., Whitney, A.M., Melles, C.E., Solari, C.A., Frasch, C.E., Mayer, L.W. Rev. Inst. Med. Trop. Sao Paulo (1998) [Pubmed]

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