The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

Rabgef1  -  RAB guanine nucleotide exchange factor...

Mus musculus

Synonyms: Rab5 GDP/GTP exchange factor, Rab5ef, Rabex-5, Rabex5, Ras negative regulator Rabex-5, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Rabgef1

  • We found that RabGEF1 (Rabex-5) binds to Ras and negatively regulates Ras activation and downstream effector pathways during FcepsilonRI-dependent mouse mast cell activation [1].


  1. RabGEF1, a negative regulator of Ras signalling, mast cell activation and skin inflammation. Tam, S.Y., Kalesnikoff, J., Nakae, S., Tsai, M., Galli, S.J. Novartis Found. Symp. (2005) [Pubmed]
WikiGenes - Universities