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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

RABGEF1  -  RAB guanine nucleotide exchange factor...

Bos taurus

 
 
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High impact information on RABEX5

 

Biological context of RABEX5

  • Rabex-5 binds monoubiquitin, undergoes covalent ubiquitination and contains an intrinsic ubiquitin ligase activity, all of which require an N-terminal A20 zinc finger followed immediately by a helix [2].

References

  1. In vitro formation of recycling vesicles from endosomes requires adaptor protein-1/clathrin and is regulated by rab4 and the connector rabaptin-5. Pagano, A., Crottet, P., Prescianotto-Baschong, C., Spiess, M. Mol. Biol. Cell (2004) [Pubmed]
  2. Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5. Lee, S., Tsai, Y.C., Mattera, R., Smith, W.J., Kostelansky, M.S., Weissman, A.M., Bonifacino, J.S., Hurley, J.H. Nat. Struct. Mol. Biol. (2006) [Pubmed]
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