Gene Review:
RABGEF1 - RAB guanine nucleotide exchange factor...
Homo sapiens
Synonyms:
RABEX5, RAP1, Rab5 GDP/GTP exchange factor, Rabaptin-5-associated exchange factor for Rab5, Rabex-5, ...
- Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin. Penengo, L., Mapelli, M., Murachelli, A.G., Confalonieri, S., Magri, L., Musacchio, A., Di Fiore, P.P., Polo, S., Schneider, T.R. Cell (2006)
- A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function. Horiuchi, H., Lippé, R., McBride, H.M., Rubino, M., Woodman, P., Stenmark, H., Rybin, V., Wilm, M., Ashman, K., Mann, M., Zerial, M. Cell (1997)
- A new side to ubiquitin. Raiborg, C., Slagsvold, T., Stenmark, H. Trends Biochem. Sci. (2006)
- The Rab5 guanine nucleotide exchange factor Rabex-5 binds ubiquitin (Ub) and functions as a Ub ligase through an atypical Ub-interacting motif and a zinc finger domain. Mattera, R., Tsai, Y.C., Weissman, A.M., Bonifacino, J.S. J. Biol. Chem. (2006)
- Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex. Lippé, R., Miaczynska, M., Rybin, V., Runge, A., Zerial, M. Mol. Biol. Cell (2001)
- Seven genes that are differentially transcribed in colorectal tumor cell lines. Nimmrich, I., Erdmann, S., Melchers, U., Finke, U., Hentsch, S., Moyer, M.P., Hoffmann, I., Müller, O. Cancer Lett. (2000)