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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Pclo  -  piccolo (presynaptic cytomatrix protein)

Rattus norvegicus

Synonyms: Aczonin, Multidomain presynaptic cytomatrix protein, Protein piccolo
 
 
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High impact information on Pclo

  • Localization of the presynaptic cytomatrix protein Piccolo at ribbon and conventional synapses in the rat retina: comparison with Bassoon [1].
  • The active zone protein Piccolo (also known as Aczonin) contains an unusual C2A domain that exhibits a low affinity for Ca2+, a Ca2+-induced conformational change and Ca2+-dependent dimerization [2].

References

  1. Localization of the presynaptic cytomatrix protein Piccolo at ribbon and conventional synapses in the rat retina: comparison with Bassoon. Dick, O., Hack, I., Altrock, W.D., Garner, C.C., Gundelfinger, E.D., Brandstätter, J.H. J. Comp. Neurol. (2001) [Pubmed]
  2. A conformational switch in the Piccolo C2A domain regulated by alternative splicing. Garcia, J., Gerber, S.H., Sugita, S., Südhof, T.C., Rizo, J. Nat. Struct. Mol. Biol. (2004) [Pubmed]
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