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Gene Review

IDDM18  -  insulin-dependent diabetes mellitus 18

Homo sapiens

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Disease relevance of IDDM18


High impact information on IDDM18

  • We report here a new susceptibility locus, IDDM18, located near the interleukin-12 (IL-12)p40 gene, IL12B [2].


  1. Interleukin-12p40 gene (IL-12B) polymorphism and Type 1 diabetes mellitus in Japanese: possible role in subjects without having high-risk HLA haplotypes. Yang, J.M., Nagasaka, S., Yatagai, T., Nakamura, T., Kusaka, I., Ishikawa, S.E., Saito, T., Ishibashi, S. Diabetes Res. Clin. Pract. (2006) [Pubmed]
  2. Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele. Morahan, G., Huang, D., Ymer, S.I., Cancilla, M.R., Stephen, K., Dabadghao, P., Werther, G., Tait, B.D., Harrison, L.C., Colman, P.G. Nat. Genet. (2001) [Pubmed]
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