Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

PLSCR2 - phospholipid scramblase 2

Homo sapiens

Synonyms: Ca(2+)-dependent phospholipid scramblase 2, PL scramblase 2, Phospholipid scramblase 2

Yu, A. et al.

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High impact information on PLSCR2

PLSCR1 was localized on the plasma membrane, whereas PLSCR2 was predominantly in the nucleus [1].
To determine whether PtdSer biosynthesis and externalization are altered by PLSCR activities during apoptosis, Chinese hamster ovary K1 cell lines stably overexpressing PLSCR1 and PLSCR2 were established [1].

References

Stimulation of phosphatidylserine biosynthesis and facilitation of UV-induced apoptosis in Chinese hamster ovary cells overexpressing phospholipid scramblase 1. Yu, A., McMaster, C.R., Byers, D.M., Ridgway, N.D., Cook, H.W. J. Biol. Chem. (2003) [Pubmed]

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