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Plscr1  -  phospholipid scramblase 1

Mus musculus

Synonyms: Ca(2+)-dependent phospholipid scramblase 1, MmTRA1a, MmTRA1b, MuPLSCR2, NOR1, ...
 
 
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Disease relevance of Plscr1

 

High impact information on Plscr1

 

Biological context of Plscr1

 

Anatomical context of Plscr1

 

Associations of Plscr1 with chemical compounds

 

Other interactions of Plscr1

  • By low stringency hybridization using the DNA binding domain of NOR-1 as a probe, a C-terminal truncated Nurr1 isoform, named Nurr2, was isolated from a mouse MC3T3-E1 cell cDNA library [8].
 

Analytical, diagnostic and therapeutic context of Plscr1

References

  1. Comparison of mechanisms of anemia in mice with sickle cell disease and beta-thalassemia: peripheral destruction, ineffective erythropoiesis, and phospholipid scramblase-mediated phosphatidylserine exposure. Kean, L.S., Brown, L.E., Nichols, J.W., Mohandas, N., Archer, D.R., Hsu, L.L. Exp. Hematol. (2002) [Pubmed]
  2. Detection of chromosomal aberrations by comparative genomic hybridization during transformation of human breast epithelial cells in vitro. Balogh, G.A., Russo, I.H., Balsara, B.R., Russo, J. Int. J. Oncol. (2006) [Pubmed]
  3. H-ras mutations at codon 61 or 13 in tumors initiated with a NO donor in mouse skin. Satomi, Y., Bu, P., Okuda, M., Tokuda, H., Nishino, H. Cancer Lett. (2003) [Pubmed]
  4. TRA1, a novel mRNA highly expressed in leukemogenic mouse monocytic sublines but not in nonleukemogenic sublines. Kasukabe, T., Okabe-Kado, J., Honma, Y. Blood (1997) [Pubmed]
  5. Stimulation of phosphatidylserine biosynthesis and facilitation of UV-induced apoptosis in Chinese hamster ovary cells overexpressing phospholipid scramblase 1. Yu, A., McMaster, C.R., Byers, D.M., Ridgway, N.D., Cook, H.W. J. Biol. Chem. (2003) [Pubmed]
  6. Localization and significance of molecular chaperones, heat shock protein 1, and tumor rejection antigen gp96 in the male reproductive tract and during capacitation and acrosome reaction. Asquith, K.L., Harman, A.J., McLaughlin, E.A., Nixon, B., Aitken, R.J. Biol. Reprod. (2005) [Pubmed]
  7. Cancer chemopreventive activity of phenylpropanoid esters of sucrose, vanicoside B and lapathoside A, from Polygonum lapathifolium. Takasaki, M., Konoshima, T., Kuroki, S., Tokuda, H., Nishino, H. Cancer Lett. (2001) [Pubmed]
  8. An isoform of Nurr1 functions as a negative inhibitor of the NGFI-B family signaling. Ohkura, N., Hosono, T., Maruyama, K., Tsukada, T., Yamaguchi, K. Biochim. Biophys. Acta (1999) [Pubmed]
  9. Comparative proteomic analysis to study molecular events during gonad development in mice. Wilhelm, D., Huang, E., Svingen, T., Stanfield, S., Dinnis, D., Koopman, P. Genesis (2006) [Pubmed]
 
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