The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • OMIM
  • SNPedia
  • UniProt
  • Ensembl
  • HGNC

Table of contents

About

Terms

 

Gene Review: 

PLSCR4  -  phospholipid scramblase 4

Homo sapiens

Synonyms: Ca(2+)-dependent phospholipid scramblase 4, Cell growth-inhibiting gene 43 protein, GIG43, PL scramblase 4, Phospholipid scramblase 4, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of PLSCR4

 

High impact information on PLSCR4

  • The phospholipid scramblases (PLSCR1 to PLSCR4) are a structurally and functionally unique class of proteins, which are products of a tetrad of genes conserved from Caenorhabditis elegans to humans [2].
  • RESULTS: NT-hESC CD34(+) count was 7.6%, viability 100%, karyotyping normal, pluripotency markers: SSEA-1, SSEA-4, OCT-3/4, TRA-1/60:positive; 12% PBC was noted at 1 week after transplantation [3].
 

Other interactions of PLSCR4

  • CONCLUSION: The intrauterine expression of PLSCR3 and PLSCR4 provides a dynamic mechanism by which aminophospholipid translocation can be regulated, thereby modulating the activity of various membrane proteins that are involved in inflammation and coagulation-related events [1].

References

  1. Phospholipid scramblase isoform expression in pregnant rat uterus. Phillippe, M., Bradley, D.F., Ji, H., Oppenheimer, K.H., Chien, E.K. J. Soc. Gynecol. Investig. (2006) [Pubmed]
  2. Adiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (PLSCR3). Wiedmer, T., Zhao, J., Li, L., Zhou, Q., Hevener, A., Olefsky, J.M., Curtiss, L.K., Sims, P.J. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  3. Embryonic stem cell derived and adult hematopoietic stem cell transplantation for tolerance induction in a renal allograft recipient:-a case report. Trivedi, H.L., Mishra, V.V., Vanikar, A.V., Modi, P.R., Shah, V.R., Shah, P.R., Firoz, A. Transplant. Proc. (2006) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities