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Gene Review:

SHROOM4 - shroom family member 4

Homo sapiens

Synonyms: KIAA1202, Protein Shroom4, SHAP, Second homolog of apical protein

Hagens, O. et al., Hagens, O. et al.

Hagens, Ballabio, Kalscheuer, Kraehenbuhl, Schiaffino, Smith, Staub, Hildebrand, Wallingford,

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Disease relevance of SHROOM4

Disruptions of the novel KIAA1202 gene are associated with X-linked mental retardation [1].

High impact information on SHROOM4

Transient expression of the wild-type KIAA1202 protein in HeLa cells showed partial colocalisation with the F-actin based cytoskeleton [1].
At present these proteins are named Shroom, APX, APXL, and KIAA1202 [2].

References

Disruptions of the novel KIAA1202 gene are associated with X-linked mental retardation. Hagens, O., Dubos, A., Abidi, F., Barbi, G., Van Zutven, L., Hoeltzenbein, M., Tommerup, N., Moraine, C., Fryns, J.P., Chelly, J., van Bokhoven, H., Gécz, J., Dollfus, H., Ropers, H.H., Schwartz, C.E., de Cassia Stocco Dos Santos, R., Kalscheuer, V., Hanauer, A. Hum. Genet. (2006) [Pubmed]
A new standard nomenclature for proteins related to Apx and Shroom. Hagens, O., Ballabio, A., Kalscheuer, V., Kraehenbuhl, J.P., Schiaffino, M.V., Smith, P., Staub, O., Hildebrand, J., Wallingford, J.B. BMC Cell Biol. (2006) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

SHROOM4	Bos taurus
SHROOM4	Canis lupus familiaris
LOC777072	Gallus gallus
SHROOM4	Macaca mulatta
Shroom4	Mus musculus
SHROOM4	Pan troglodytes
Shroom4	Rattus norvegicus

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