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Gene Review:

RAB27B - RAB27B, member RAS oncogene family

Homo sapiens

Synonyms: C25KG, Ras-related protein Rab-27B

Ramalho, J.S. et al., Fujii, M. et al.

Ramalho, Tolmachova, Hume, McGuigan, Gregory-Evans, Huxley, Seabra,

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High impact information on RAB27B

The up-regulation of RAB27B depends on the p53 gene [1].
As with RAB27A in Griscelli Disease, RAB27B may be also associated with human disease mapping to chromosome 18 [2].
RESULTS: The human RAB27B gene is organised in six exons, spanning about 69 kb in the chromosome 18q21.1 region [2].

References

Expression of RAB27B is up-regulated in senescent human cells. Fujii, M., Kawai, Y., Endoh, M., Hossain, M.N., Nakabayashi, K., Ayusawa, D. Mech. Ageing Dev. (2006) [Pubmed]
Chromosomal mapping, gene structure and characterization of the human and murine RAB27B gene. Ramalho, J.S., Tolmachova, T., Hume, A.N., McGuigan, A., Gregory-Evans, C.Y., Huxley, C., Seabra, M.C. BMC Genet. (2001) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

RAB27B	Bos taurus
RAB27B	Canis lupus familiaris
si:ch1073-112i17.1	Danio rerio
RAB27B	Macaca mulatta
Rab27b	Mus musculus
RAB27B	Pan troglodytes
Rab27b	Rattus norvegicus
rab27b	Xenopus (Silurana) tropicalis

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