The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

RAP2B  -  RAP2B, member of RAS oncogene family

Homo sapiens

Synonyms: Ras-related protein Rap-2b
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of RAP2B


High impact information on RAP2B

  • RAP2B is 90% identical to RAP2 at the amino acid level with the most variability at the carboxyl terminus of the protein [1].
  • Moreover, incubation of similar extracts with the catalytic subunit of cAMP-dependent protein kinase did not cause phosphorylation of RAP2B, as had been observed for the closely homologous proteins, RAP1A and RAP1B [1].
  • A repeated screening of the platelet cDNA library with an internal Ava I fragment of the RAP2B cDNA allowed the isolation of a full-length cDNA for the RAP2B sequence [1].


  1. RAP2B: a RAS-related GTP-binding protein from platelets. Ohmstede, C.A., Farrell, F.X., Reep, B.R., Clemetson, K.J., Lapetina, E.G. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
WikiGenes - Universities