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Gene Review

SENP2  -  SUMO1/sentrin/SMT3 specific peptidase 2

Homo sapiens

Synonyms: AXAM2, Axam2, DKFZp762A2316, KIAA1331, SMT3-specific isopeptidase 2, ...
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Disease relevance of SENP2

  • The SMT3IP2 expressed by Escherichia coli could cleave SUMO-1, Smt3a, or Smt3b from a SUMO-1/RanGAP1, Smt3a/RanGAP1, or Smt3b/RanGAP1 conjugate, respectively, and had the activity of a carboxyl-terminal hydrolase to produce a glycine residue in the carboxyl terminus of these ubiquitin-like proteins [1].

High impact information on SENP2


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