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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Senp2  -  SUMO/sentrin specific peptidase 2

Mus musculus

Synonyms: 2310007L05Rik, 4930538C18Rik, AI646780, AW554757, Axam2, ...
 
 
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Disease relevance of Senp2

 

High impact information on Senp2

  • We identify experimentally three consensus SUMO attachment sites, two in the N-terminal transactivation region and one in the ligand-binding domain of GR [2].
  • We report that mouse Sox2 is modified by SUMO at lysine 247 [3].

References

  1. Yersinia lead SUMO attack. Cornelis, G.R., Denecker, G. Nat. Med. (2001) [Pubmed]
  2. Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor. Tian, S., Poukka, H., Palvimo, J.J., Jänne, O.A. Biochem. J. (2002) [Pubmed]
  3. Inhibition of DNA binding of Sox2 by the SUMO conjugation. Tsuruzoe, S., Ishihara, K., Uchimura, Y., Watanabe, S., Sekita, Y., Aoto, T., Saitoh, H., Yuasa, Y., Niwa, H., Kawasuji, M., Baba, H., Nakao, M. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
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