The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

pax5  -  paired box 5

Danio rerio

Synonyms: Pax[Zf-b], SO:0000704, noi, pax2.1, pax2a, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on pax5

  • Anterior markers pax5 and nkx5.1 are expressed in expanded domains that include the entire otic epithelium juxtaposed to the hindbrain, and the posterior marker zp23 is not expressed [1].
  • Otic expression of pax5 requires pax2a and fgf3, mutations in which cause vestibular defects, albeit by distinct mechanisms [2].


  1. An expanded domain of fgf3 expression in the hindbrain of zebrafish valentino mutants results in mis-patterning of the otic vesicle. Kwak, S.J., Phillips, B.T., Heck, R., Riley, B.B. Development (2002) [Pubmed]
  2. Zebrafish pax5 regulates development of the utricular macula and vestibular function. Kwak, S.J., Vemaraju, S., Moorman, S.J., Zeddies, D., Popper, A.N., Riley, B.B. Dev. Dyn. (2006) [Pubmed]
WikiGenes - Universities