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Gene Review

pax6b  -  paired box 6b

Danio rerio

Synonyms: Pax6.2, SO:0000704, cb566, fc09c10, id:ibd5095, ...
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High impact information on pax6b

  • Additionally, stage-matched zebrafish embryos having decreased pax6a and/or pax6b activity display malformed rhombomere boundaries and an anteriorized hoxd4a expression border [1].
  • The embryonic expression patterns of Pax6.1 and Pax6.2 reveal both overlapping and discrete expression domains suggesting a division of labor between these two very similar gene products during development of brain and eye structures [2].


  1. Stereospecificity and PAX6 function direct Hoxd4 neural enhancer activity along the antero-posterior axis. Nolte, C., Rastegar, M., Amores, A., Bouchard, M., Grote, D., Maas, R., Kovacs, E.N., Postlethwait, J., Rambaldi, I., Rowan, S., Yan, Y.L., Zhang, F., Featherstone, M. Dev. Biol. (2006) [Pubmed]
  2. Zebrafish contains two pax6 genes involved in eye development. Nornes, S., Clarkson, M., Mikkola, I., Pedersen, M., Bardsley, A., Martinez, J.P., Krauss, S., Johansen, T. Mech. Dev. (1998) [Pubmed]
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