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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Gosr2  -  golgi SNAP receptor complex member 2

Rattus norvegicus

Synonyms: 27 kDa Golgi SNARE protein, Golgi SNAP receptor complex member 2, Gs27, Membrin
 
 
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High impact information on Gosr2

  • The ER/Golgi soluble NSF attachment protein receptor (SNARE) membrin, rsec22b, and rbet1 are enriched in approximately 1-micrometer cytoplasmic structures that lie very close to the ER [1].
  • Here we demonstrate that hsc70 chaperones stimulate in vitro SNARE complex formation among the ER/Golgi SNAREs syntaxin 5, membrin, rbetl and sec22b, under conditions in which assembly is normally inhibited [2].

References

  1. SNARE membrane trafficking dynamics in vivo. Chao, D.S., Hay, J.C., Winnick, S., Prekeris, R., Klumperman, J., Scheller, R.H. J. Cell Biol. (1999) [Pubmed]
  2. Evidence for regulation of ER/Golgi SNARE complex formation by hsc70 chaperones. Joglekar, A.P., Hay, J.C. Eur. J. Cell Biol. (2005) [Pubmed]
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