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Gene Review

WDR13  -  WD repeat domain 13

Homo sapiens

Synonyms: WD repeat-containing protein 13
 
 
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High impact information on WDR13

  • All three antibodies mediate antibody-dependent cellular cytotoxicity (ADCC) in vitro when tested with human lymphocytes as effector cells in a 2-hr or 4-hr 51Cr-release test, and one antibody, MG-21, also gives strong complement-dependent cytotoxicity with human serum [1].
  • A highly conserved human gene encoding a novel member of WD-repeat family of proteins (WDR13) [2].
 

Biological context of WDR13

References

  1. Strong antitumor activities of IgG3 antibodies to a human melanoma-associated ganglioside. Hellström, I., Brankovan, V., Hellström, K.E. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
  2. A highly conserved human gene encoding a novel member of WD-repeat family of proteins (WDR13). Singh, B.N., Suresh, A., UmaPrasad, G., Subramanian, S., Sultana, M., Goel, S., Kumar, S., Singh, L. Genomics (2003) [Pubmed]
 
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