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Gene Review

SNAPC2  -  small nuclear RNA activating complex,...

Homo sapiens

Synonyms: PSE-binding factor subunit delta, PTF subunit delta, PTFDELTA, PTFdelta, Proximal sequence element-binding transcription factor subunit delta, ...
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High impact information on SNAPC2

  • The SNAP45 subunit of the small nuclear RNA (snRNA) activating protein complex is required for RNA polymerase II and III snRNA gene transcription and interacts with the TATA box binding protein [1].
  • SNAP190 is required for snRNA gene transcription by both RNA polymerases II and III and interacts with SNAP45 [2].
  • We now report the isolation and expression of cDNAs encoding PTF gamma and PTF delta, as well as functional studies with cognate antibodies that recognize the native PTF complex in HeLa extracts [3].


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