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Gene Review

SNRPD2  -  small nuclear ribonucleoprotein D2...

Homo sapiens

Synonyms: SMD2, SNRPD1, Sm-D2, Small nuclear ribonucleoprotein Sm D2, snRNP core protein D2
 
 
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High impact information on SNRPD2

  • Gemin3 interacts directly with SMN, as well as with SmB, SmD2, and SmD3 [1].
  • We define the common antigenic targets of Sm D2 and D3 and examine their role in spliceosomal autoimmunity [2].

References

  1. Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems. Charroux, B., Pellizzoni, L., Perkinson, R.A., Shevchenko, A., Mann, M., Dreyfuss, G. J. Cell Biol. (1999) [Pubmed]
  2. Anti-sm autoantibodies in systemic lupus target highly basic surface structures of complexed spliceosomal autoantigens. McClain, M.T., Ramsland, P.A., Kaufman, K.M., James, J.A. J. Immunol. (2002) [Pubmed]
 
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