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Gene Review

Zdhhc1  -  zinc finger, DHHC domain containing 1

Mus musculus

Synonyms: 4432412D04Rik, DHHC-1, Zinc finger DHHC domain-containing protein 1
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High impact information on Zdhhc1

  • Here, we isolated 23 mammalian DHHC proteins and found that a subset specifically palmitoylated PSD-95 in vitro and in vivo [1].

Associations of Zdhhc1 with chemical compounds

  • The enzymes that mediate palmitoyl acyl transfer to PSD-95 have not yet been identified; however, proteins containing a DHHC cysteine-rich domain mediate palmitoyl acyl transferase activity in yeast [1].


  1. Identification of PSD-95 palmitoylating enzymes. Fukata, M., Fukata, Y., Adesnik, H., Nicoll, R.A., Bredt, D.S. Neuron (2004) [Pubmed]
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