Gene Review:
Dlg4 - discs, large homolog 4 (Drosophila)
Mus musculus
Synonyms:
Disks large homolog 4, Dlgh4, PSD-95, PSD95, Postsynaptic density protein 95, ...
- Neuropathic sensitization of behavioral reflexes and spinal NMDA receptor/CaM kinase II interactions are disrupted in PSD-95 mutant mice. Garry, E.M., Moss, A., Delaney, A., O'Neill, F., Blakemore, J., Bowen, J., Husi, H., Mitchell, R., Grant, S.G., Fleetwood-Walker, S.M. Curr. Biol. (2003)
- The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95. Todd, P.K., Mack, K.J., Malter, J.S. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Identification of PSD-95 palmitoylating enzymes. Fukata, M., Fukata, Y., Adesnik, H., Nicoll, R.A., Bredt, D.S. Neuron (2004)
- Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. Yao, W.D., Gainetdinov, R.R., Arbuckle, M.I., Sotnikova, T.D., Cyr, M., Beaulieu, J.M., Torres, G.E., Grant, S.G., Caron, M.G. Neuron (2004)
- Synapse formation by hippocampal neurons from agrin-deficient mice. Serpinskaya, A.S., Feng, G., Sanes, J.R., Craig, A.M. Dev. Biol. (1999)
- Differential expression of two NMDA receptor interacting proteins, PSD-95 and SynGAP during mouse development. Porter, K., Komiyama, N.H., Vitalis, T., Kind, P.C., Grant, S.G. Eur. J. Neurosci. (2005)
- Differential expression of alternatively spliced isoforms of neuronal nitric oxide synthase (nNOS) and N-methyl-D-aspartate receptors (NMDAR) in knockout mice deficient in nNOS alpha (nNOS alpha(Delta/Delta) mice). Putzke, J., Seidel, B., Huang, P.L., Wolf, G. Brain Res. Mol. Brain Res. (2000)
- Slo2 sodium-activated K+ channels bind to the PDZ domain of PSD-95. Uchino, S., Wada, H., Honda, S., Hirasawa, T., Yanai, S., Nakamura, Y., Ondo, Y., Kohsaka, S. Biochem. Biophys. Res. Commun. (2003)
- Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse. Welch, J.M., Wang, D., Feng, G. J. Comp. Neurol. (2004)
- Improved immunohistochemical detection of postsynaptically located PSD-95/SAP90 protein family by protease section pretreatment: a study in the adult mouse brain. Fukaya, M., Watanabe, M. J. Comp. Neurol. (2000)
- Regulation of dendritic branching and spine maturation by semaphorin3A-Fyn signaling. Morita, A., Yamashita, N., Sasaki, Y., Uchida, Y., Nakajima, O., Nakamura, F., Yagi, T., Taniguchi, M., Usui, H., Katoh-Semba, R., Takei, K., Goshima, Y. J. Neurosci. (2006)
- Citron, a Rho-target, interacts with PSD-95/SAP-90 at glutamatergic synapses in the thalamus. Furuyashiki, T., Fujisawa, K., Fujita, A., Madaule, P., Uchino, S., Mishina, M., Bito, H., Narumiya, S. J. Neurosci. (1999)
- Identification of PSD-93 as a substrate for the Src family tyrosine kinase Fyn. Nada, S., Shima, T., Yanai, H., Husi, H., Grant, S.G., Okada, M., Akiyama, T. J. Biol. Chem. (2003)
- Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses. Almeida, C.G., Tampellini, D., Takahashi, R.H., Greengard, P., Lin, M.T., Snyder, E.M., Gouras, G.K. Neurobiol. Dis. (2005)
- Microtubule-associated protein light chain 2 is a stargazin-AMPA receptor complex-interacting protein in vivo. Ives, J.H., Fung, S., Tiwari, P., Payne, H.L., Thompson, C.L. J. Biol. Chem. (2004)
- SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor. Komiyama, N.H., Watabe, A.M., Carlisle, H.J., Porter, K., Charlesworth, P., Monti, J., Strathdee, D.J., O'Carroll, C.M., Martin, S.J., Morris, R.G., O'Dell, T.J., Grant, S.G. J. Neurosci. (2002)
- Neonatal hypoxia-ischemia differentially upregulates MAGUKs and associated proteins in PSD-93-deficient mouse brain. Jiang, X., Mu, D., Sheldon, R.A., Glidden, D.V., Ferriero, D.M. Stroke (2003)
- Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons. Morabito, M.A., Sheng, M., Tsai, L.H. J. Neurosci. (2004)
- G-protein-coupled receptor modulation of striatal CaV1.3 L-type Ca2+ channels is dependent on a Shank-binding domain. Olson, P.A., Tkatch, T., Hernandez-Lopez, S., Ulrich, S., Ilijic, E., Mugnaini, E., Zhang, H., Bezprozvanny, I., Surmeier, D.J. J. Neurosci. (2005)
- A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin. Prange, O., Wong, T.P., Gerrow, K., Wang, Y.T., El-Husseini, A. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Isolation of 2000-kDa complexes of N-methyl-D-aspartate receptor and postsynaptic density 95 from mouse brain. Husi, H., Grant, S.G. J. Neurochem. (2001)
- Age-related loss of synapses in the frontal cortex of SAMP10 mouse: a model of cerebral degeneration. Shimada, A., Keino, H., Satoh, M., Kishikawa, M., Hosokawa, M. Synapse (2003)
- Environmental enrichment results in cortical and subcortical changes in levels of synaptophysin and PSD-95 proteins. Nithianantharajah, J., Levis, H., Murphy, M. Neurobiology of learning and memory. (2004)
- Synaptic targeting by Alzheimer's-related amyloid beta oligomers. Lacor, P.N., Buniel, M.C., Chang, L., Fernandez, S.J., Gong, Y., Viola, K.L., Lambert, M.P., Velasco, P.T., Bigio, E.H., Finch, C.E., Krafft, G.A., Klein, W.L. J. Neurosci. (2004)