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Gene Review:

Pex13 - peroxisomal biogenesis factor 13

Mus musculus

Synonyms: 2610008O20Rik, Peroxin-13, Peroxisomal membrane protein PEX13

Björkman, J. et al., Geuze, H.J. et al., Bjorkman, J. et al.

Geuze, Murk, Stroobants, Griffith, Kleijmeer, Koster, Verkleij, Distel, Tabak,

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High impact information on Pex13

We found the peroxisomal membrane protein Pex13p and the ATP-binding cassette transporter protein PMP70 present in specialized subdomains of the ER that were continuous with a peroxisomal reticulum from which mature peroxisomes arose [1].
Conditional inactivation of the peroxisome biogenesis Pex13 gene by Cre-loxP excision [2].
Mouse Pex13 spans 18 kb and consists of four exons [3].
We detected Pex13 transcripts in all mouse tissues tested, with highest levels in liver and testis [3].
The Pex13 open reading frame predicts a 44.5-kDa protein that displays 91% sequence identity to the human PEX13 protein [3].

References

Involvement of the endoplasmic reticulum in peroxisome formation. Geuze, H.J., Murk, J.L., Stroobants, A.K., Griffith, J.M., Kleijmeer, M.J., Koster, A.J., Verkleij, A.J., Distel, B., Tabak, H.F. Mol. Biol. Cell (2003) [Pubmed]
Conditional inactivation of the peroxisome biogenesis Pex13 gene by Cre-loxP excision. Bjorkman, J., Tonks, I., Maxwell, M.A., Paterson, C., Kay, G.F., Crane, D.I. Genesis (2002) [Pubmed]
Pex13, the mouse ortholog of the human peroxisome biogenesis disorder PEX13 gene: gene structure, tissue expression, and localization of the protein to peroxisomes. Björkman, J., Gould, S.J., Crane, D.I. Genomics (2002) [Pubmed]

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AgaP_AGAP010074	Anopheles gambiae str. PEST
PEX13	Bos taurus
prx-13	Caenorhabditis elegans
PEX13	Canis lupus familiaris
pex13	Danio rerio
Pex13	Drosophila melanogaster
PEX13	Gallus gallus
PEX13	Homo sapiens
PEX13	Macaca mulatta
PEX13	Pan troglodytes
Pex13	Rattus norvegicus
pex13	Xenopus (Silurana) tropicalis

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