Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

Dpp3 - dipeptidylpeptidase 3

Mus musculus

Synonyms: 4930533O14Rik, C86324, DPP III, Dipeptidyl aminopeptidase III, Dipeptidyl arylamidase III, ...

Swanson, A.A. et al., Allard, M. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Dpp3

An arylamidase-like activity could also be participating in [3H]AII hydrolysis, because higher concentrations of bestatin (10(-4) M) in association with dipeptidyl aminopeptidase III inhibitors totally inhibited [3H]tyrosine formation, increased protection of [3H]AII and [3H]AII1-7 formed, and provoked a slight accumulation of [3H]AII2-8 [1].
Dipeptidyl aminopeptidase III (EC 3.4.14.4) could play a critical role, as suggested by the formation of [3H]Val3-Tyr4 and [3H]-Tyr4-Ile5 in the presence of bestatin (2 X 10(-5) M) [1].
Exopeptidases identified as dipeptidyl peptidase III and leucine aminopeptidase, and an endopeptidase, prolyl endopeptidase, were found in the Emory Mouse cataract and the Cataract Resistant mouse lens extracts [2].

Associations of Dpp3 with chemical compounds

The specific activity measured on Arg-Arg-2-NNap for DPP III and the hydrolysis of Boc-Arg-Pro-2-NNap for prolyl endopeptidase were higher in the Emory Mouse cataractous lens extract [2].

References

Angiotensin II inactivation process in cultured mouse spinal cord cells. Allard, M., Simonnet, G., Dupouy, B., Vincent, J.D. J. Neurochem. (1987) [Pubmed]
Proteases in the Emory mouse cataract. Swanson, A.A., Davis, R.M., Meinhardt, N.C., Kuck, K.D., Kuck, J.F. Invest. Ophthalmol. Vis. Sci. (1985) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AgaP_AGAP004394	Anopheles gambiae str. PEST
AGOS_AER229C	Ashbya gossypii ATCC 10895
DPP3	Bos taurus
CELE_F02E9.9	Caenorhabditis elegans
DPP3	Canis lupus familiaris
dpp3	Danio rerio
DppIII	Drosophila melanogaster
DPP3	Homo sapiens
KLLA0C04059g	Kluyveromyces lactis NRRL Y-1140
DPP3	Macaca mulatta
MGG_04445	Magnaporthe oryzae 70-15
NCU02701	Neurospora crassa OR74A
DPP3	Pan troglodytes
Dpp3	Rattus norvegicus
YOL057W	Saccharomyces cerevisiae S288c
dpp3	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.