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Gene Review

Mnd1  -  meiotic nuclear divisions 1 homolog (S....

Mus musculus

Synonyms: 2610034E18Rik, AI591601, Gaj, Meiotic nuclear division protein 1 homolog
 
 
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High impact information on Mnd1

  • These results suggest that Hop2 and Mnd1 work as a complex to promote meiotic chromosome pairing and DSB repair [1].
  • Here we show that mouse Hop2 can efficiently form D-loops, the first recombination intermediates, but this activity is abrogated upon association with Mnd1 [2].

References

  1. The Mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair. Tsubouchi, H., Roeder, G.S. Mol. Cell. Biol. (2002) [Pubmed]
  2. The Hop2 and Mnd1 proteins act in concert with Rad51 and Dmc1 in meiotic recombination. Petukhova, G.V., Pezza, R.J., Vanevski, F., Ploquin, M., Masson, J.Y., Camerini-Otero, R.D. Nat. Struct. Mol. Biol. (2005) [Pubmed]
 
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