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Gene Review

GALNT14  -  polypeptide N-acetylgalactosaminyltransfer...

Homo sapiens

Synonyms: FLJ12691, GALNT15, GalNAc-T14, GalNac-T10, GalNac-T14, ...
 
 
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High impact information on GALNT14

 

Analytical, diagnostic and therapeutic context of GALNT14

  • Quantitative real time PCR analysis revealed significantly high expression of the pp-GalNAc-T14 transcript in kidney, although the transcripts were ubiquitously expressed in all tissues examined [1].
  • SNPs on GALNT14 was found to be associated to chemotherapy response of hepatocellular carcinoma patients [2].

References

  1. Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14. Wang, H., Tachibana, K., Zhang, Y., Iwasaki, H., Kameyama, A., Cheng, L., Guo, J., Hiruma, T., Togayachi, A., Kudo, T., Kikuchi, N., Narimatsu, H. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
  2. GALNT14 SNP as a potential predictor of response to combination chemotherapy using 5-FU, mitoxantrone and cisplatin in advanced HCC. Liang, K.H., Lin, C.C., Yeh, C.T. Pharmacogenomics. (2011) [Pubmed]
 
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