The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

CHPF  -  chondroitin polymerizing factor

Homo sapiens

Synonyms: CHSY2, CSS2, ChPF, Chondroitin glucuronyltransferase 2, Chondroitin sulfate synthase 2, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of CHPF


High impact information on CHPF


Biological context of CHPF


Anatomical context of CHPF


Associations of CHPF with chemical compounds


Enzymatic interactions of CHPF


Other interactions of CHPF


Analytical, diagnostic and therapeutic context of CHPF


  1. Expression of UDP-GalNAc:NeuAc alpha 2,3Gal beta-R beta 1,4(GalNAc to Gal) N-acetylgalactosaminyltransferase involved in the synthesis of Sda antigen in human large intestine and colorectal carcinomas. Malagolini, N., Dall'Olio, F., Di Stefano, G., Minni, F., Marrano, D., Serafini-Cessi, F. Cancer Res. (1989) [Pubmed]
  2. Increased sensitivity of gastric cancer cells to natural killer and lymphokine-activated killer cells by antisense suppression of N-acetylgalactosaminyltransferase. Adachi, T., Hinoda, Y., Nishimori, I., Adachi, M., Imai, K. J. Immunol. (1997) [Pubmed]
  3. The Role of Mutant UDP-N-Acetyl-{alpha}-D-Galactosamine-Polypeptide N-Acetylgalactosaminyltransferase 3 in Regulating Serum Intact Fibroblast Growth Factor 23 and Matrix Extracellular Phosphoglycoprotein in Heritable Tumoral Calcinosis. Garringer, H.J., Fisher, C., Larsson, T.E., Davis, S.I., Koller, D.L., Cullen, M.J., Draman, M.S., Conlon, N., Jain, A., Fedarko, N.S., Dasgupta, B., White, K.E. J. Clin. Endocrinol. Metab. (2006) [Pubmed]
  4. UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (ppGalNAc-T6) mRNA as a potential new marker for detection of bone marrow-disseminated breast cancer cells. Freire, T., Berois, N., Sóñora, C., Varangot, M., Barrios, E., Osinaga, E. Int. J. Cancer (2006) [Pubmed]
  5. A cluster of basic amino acids within an alpha-helix is essential for alpha-subunit recognition by the glycoprotein hormone N-acetylgalactosaminyltransferase. Mengeling, B.J., Manzella, S.M., Baenziger, J.U. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
  6. Molecular cloning and functional characterization of a Lepidopteran insect beta4-N-acetylgalactosaminyltransferase with broad substrate specificity, a functional role in glycoprotein biosynthesis, and a potential functional role in glycolipid biosynthesis. Vadaie, N., Jarvis, D.L. J. Biol. Chem. (2004) [Pubmed]
  7. Molecular cloning of a chondroitin polymerizing factor that cooperates with chondroitin synthase for chondroitin polymerization. Kitagawa, H., Izumikawa, T., Uyama, T., Sugahara, K. J. Biol. Chem. (2003) [Pubmed]
  8. Cloning of a human UDP-N-acetyl-alpha-D-Galactosamine:polypeptide N-acetylgalactosaminyltransferase that complements other GalNAc-transferases in complete O-glycosylation of the MUC1 tandem repeat. Bennett, E.P., Hassan, H., Mandel, U., Mirgorodskaya, E., Roepstorff, P., Burchell, J., Taylor-Papadimitriou, J., Hollingsworth, M.A., Merkx, G., van Kessel, A.G., Eiberg, H., Steffensen, R., Clausen, H. J. Biol. Chem. (1998) [Pubmed]
  9. Nematode chondroitin polymerizing factor showing cell-/organ-specific expression is indispensable for chondroitin synthesis and embryonic cell division. Izumikawa, T., Kitagawa, H., Mizuguchi, S., Nomura, K.H., Nomura, K., Tamura, J., Gengyo-Ando, K., Mitani, S., Sugahara, K. J. Biol. Chem. (2004) [Pubmed]
  10. Structure-function analysis of the UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase. Essential residues lie in a predicted active site cleft resembling a lactose repressor fold. Hagen, F.K., Hazes, B., Raffo, R., deSa, D., Tabak, L.A. J. Biol. Chem. (1999) [Pubmed]
  11. Organization of a human UDP-GalNAc:polypeptide, N-acetylgalactosaminyltransferase gene and a related processed pseudogene. Meurer, J.A., Drong, R.F., Homa, F.L., Slightom, J.L., Elhammer, A.P. Glycobiology (1996) [Pubmed]
  12. A murine cytotoxic T lymphocyte cell line resistant to Vicia villosa lectin is deficient in UDP-GalNAc:beta-galactose beta 1,4-N-acetylgalactosaminyltransferase. Conzelmann, A., Kornfeld, S. J. Biol. Chem. (1984) [Pubmed]
  13. Porcine A blood group-specific N-acetylgalactosaminyltransferase. I. Purification from porcine submaxillary glands. Schwyzer, M., Hill, R.L. J. Biol. Chem. (1977) [Pubmed]
  14. Human blood group glycosyltransferases. I. Purification of n-acetylgalactosaminyltransferase. Nagai, M., Davè, V., Kaplan, B.E., Yoshida, A. J. Biol. Chem. (1978) [Pubmed]
  15. Expression of UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase isozyme 3 in the subserosal layer correlates with postsurgical survival of pathological tumor stage 2 carcinoma of the gallbladder. Miyahara, N., Shoda, J., Kawamoto, T., Furukawa, M., Ueda, T., Todoroki, T., Tanaka, N., Matsuo, K., Yamada, Y., Kohno, K., Irimura, T. Clin. Cancer Res. (2004) [Pubmed]
  16. Substrate specificity and distribution of UDP-GalNAc:sialylparagloboside N-acetylgalactosaminyltransferase in the human stomach. Dohi, T., Nishikawa, A., Ishizuka, I., Totani, M., Yamaguchi, K., Nakagawa, K., Saitoh, O., Ohshiba, S., Oshima, M. Biochem. J. (1992) [Pubmed]
  17. Chondroitin sulfate synthase-2. Molecular cloning and characterization of a novel human glycosyltransferase homologous to chondroitin sulfate glucuronyltransferase, which has dual enzymatic activities. Yada, T., Gotoh, M., Sato, T., Shionyu, M., Go, M., Kaseyama, H., Iwasaki, H., Kikuchi, N., Kwon, Y.D., Togayachi, A., Kudo, T., Watanabe, H., Narimatsu, H., Kimata, K. J. Biol. Chem. (2003) [Pubmed]
  18. Molecular cloning and expression of a second chondroitin N-acetylgalactosaminyltransferase involved in the initiation and elongation of chondroitin/dermatan sulfate. Uyama, T., Kitagawa, H., Tanaka, J., Tamura, J., Ogawa, T., Sugahara, K. J. Biol. Chem. (2003) [Pubmed]
  19. Enzymatic synthesis of chondroitin with a novel chondroitin sulfate N-acetylgalactosaminyltransferase that transfers N-acetylgalactosamine to glucuronic acid in initiation and elongation of chondroitin sulfate synthesis. Gotoh, M., Sato, T., Akashima, T., Iwasaki, H., Kameyama, A., Mochizuki, H., Yada, T., Inaba, N., Zhang, Y., Kikuchi, N., Kwon, Y.D., Togayachi, A., Kudo, T., Nishihara, S., Watanabe, H., Kimata, K., Narimatsu, H. J. Biol. Chem. (2002) [Pubmed]
  20. Purification and characterization of UDP-N-acetylgalactosamine: globotriaosylceramide beta-3-N-acetylgalactosaminyltransferase, a synthase of human blood group P antigen, from canine spleen. Taniguchi, N., Makita, A. J. Biol. Chem. (1984) [Pubmed]
  21. Preparation and enzymatic degradation of monosulfogangliotriaosylceramide. Ishizuka, I., Nagai, K., Kawaguchi, K., Tadano-Aritomi, K., Toida, T., Hirabayashi, Y., Li, Y.T., Li, S.C. J. Biol. Chem. (1985) [Pubmed]
  22. Chondroitin sulfate synthase-3. Molecular cloning and characterization. Yada, T., Sato, T., Kaseyama, H., Gotoh, M., Iwasaki, H., Kikuchi, N., Kwon, Y.D., Togayachi, A., Kudo, T., Watanabe, H., Narimatsu, H., Kimata, K. J. Biol. Chem. (2003) [Pubmed]
  23. Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14. Wang, H., Tachibana, K., Zhang, Y., Iwasaki, H., Kameyama, A., Cheng, L., Guo, J., Hiruma, T., Togayachi, A., Kudo, T., Kikuchi, N., Narimatsu, H. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
  24. A single point mutation reverses the donor specificity of human blood group B-synthesizing galactosyltransferase. Marcus, S.L., Polakowski, R., Seto, N.O., Leinala, E., Borisova, S., Blancher, A., Roubinet, F., Evans, S.V., Palcic, M.M. J. Biol. Chem. (2003) [Pubmed]
  25. Differential distribution of calpain small subunit 1 and 2 in rat brain. Friedrich, P., Papp, H., Halasy, K., Farkas, A., Farkas, B., Tompa, P., Kása, P. Eur. J. Neurosci. (2004) [Pubmed]
WikiGenes - Universities