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Gene Review

RHBDF2  -  rhomboid 5 homolog 2 (Drosophila)

Homo sapiens

Synonyms: FLJ22341, IRHOM2, Inactive rhomboid protein 2, RHBDL5, RHBDL6, ...
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High impact information on RHBDF2

  • The proximal repeat sequence of D17S801 occurs 8 Kb upstream of the putative promoter region of FLJ22341 [1].
  • RT-PCR analysis of 8 known or strongly predicted genes residing in the MRD in 10 EOC samples, that exhibited LOH of the MRD, identified FLJ22341 as a strong candidate TSG [1].


  1. Loss of heterozygosity and transcriptome analyses of a 1.2 Mb candidate ovarian cancer tumor suppressor locus region at 17q25.1-q25.2. Presneau, N., Dewar, K., Forgetta, V., Provencher, D., Mes-Masson, A.M., Tonin, P.N. Mol. Carcinog. (2005) [Pubmed]
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