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Gene Review

MICALL2  -  MICAL-like 2

Homo sapiens

Synonyms: FLJ23471, JRAB, Junctional Rab13-binding protein, MGC46023, MICAL-L2, ...
 
 
 
 
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High impact information on MICALL2

  • Immunoprecipitation and immunofluorescence microscopy showed that MICAL-L2 specifically bound to the GTP-bound form of Rab13 via its C terminus, which contained a coiled-coil domain, and localized at TJs in epithelial MTD-1A cells [1].
  • MICAL-L2 was displaced from TJs upon actin depolymerization and was distributed along radiating actin cables and stress fibers in Ca(2+)-depleted MTD-1A and fibroblastic NIH3T3 cells, respectively [1].
 

Other interactions of MICALL2

References

  1. JRAB/MICAL-L2 Is a Junctional Rab13-binding Protein Mediating the Endocytic Recycling of Occludin. Terai, T., Nishimura, N., Kanda, I., Yasui, N., Sasaki, T. Mol. Biol. Cell (2006) [Pubmed]
 
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