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Gene Review

FAM188A  -  family with sequence similarity 188, member A

Homo sapiens

Synonyms: C10orf97, CARP, DERP5, Dermal papilla-derived protein 5, FLJ13397, ...
 
 
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Disease relevance of C10orf97

 

High impact information on C10orf97

  • We found no significant correlations between the RAST levels against Derp 2 and either Derp 5 or 7, and RAST-inhibition tests indicated a lack of cross-reactivity between Der p 2 and the other two allergens [2].
 

Analytical, diagnostic and therapeutic context of C10orf97

  • Protein sequence analysis revealed that Arpp is homologous (52.7% identity) to Carp which is shown to be involved in the regulation of the transcription of the cardiac ventricular myosin light chain 2 gene [3].

References

  1. Multiple sclerosis-associated agent: transmission to animals and some properties of the agent. Koldovsky, U., Koldovsky, P., Henle, G., Henle, W., Ackermann, R., Haase, G. Infect. Immun. (1975) [Pubmed]
  2. Biological activity of recombinant Der p 2, Der p 5 and Der p 7 allergens of the house-dust mite Dermatophagoides pteronyssinus. Lynch, N.R., Thomas, W.R., Garcia, N.M., Di Prisco, M.C., Puccio, F.A., L'opez, R.I., Hazell, L.A., Shen, H.D., Lin, K.L., Chua, K.Y. Int. Arch. Allergy Immunol. (1997) [Pubmed]
  3. Identification of a novel human ankyrin-repeated protein homologous to CARP. Moriyama, M., Tsukamoto, Y., Fujiwara, M., Kondo, G., Nakada, C., Baba, T., Ishiguro, N., Miyazaki, A., Nakamura, K., Hori, N., Sato, K., Shomori, K., Takeuchi, K., Satoh, H., Mori, S., Ito, H. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
 
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