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Gene Review

TOM3  -  tobamovirus multiplication protein 3

Arabidopsis thaliana

Synonyms: F5O4.5, F5O4_5
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High impact information on TOM3

  • Positional cloning showed that TOM3 was one of two TOM1-like genes in Arabidopsis [1].
  • As TOM1 and TOM3 homologues are present in a variety of plant species, their inhibition via RNA interference should constitute a useful method for generating tobamovirus-resistant plants [2].

Biological context of TOM3


  1. Complete inhibition of tobamovirus multiplication by simultaneous mutations in two homologous host genes. Yamanaka, T., Imai, T., Satoh, R., Kawashima, A., Takahashi, M., Tomita, K., Kubota, K., Meshi, T., Naito, S., Ishikawa, M. J. Virol. (2002) [Pubmed]
  2. Tobamovirus-resistant tobacco generated by RNA interference directed against host genes. Asano, M., Satoh, R., Mochizuki, A., Tsuda, S., Yamanaka, T., Nishiguchi, M., Hirai, K., Meshi, T., Naito, S., Ishikawa, M. FEBS Lett. (2005) [Pubmed]
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