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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

PIL5  -  transcription factor PIF1

Arabidopsis thaliana

Synonyms: PHY-INTERACTING FACTOR 1, PIF1, T2G17.2, T2G17_2, phytochrome interacting factor 3-like 5
 
 
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High impact information on PIL5

  • CONCLUSIONS: We conclude that SPT and PIL5 form part of a regulatory network coupling seed germination and GA3ox expression to light and temperature signaling in the seed [1].
  • Expression analysis revealed that PIL5 repressed the expression of GA biosynthetic genes (GA3ox1 and GA3ox2), and activated the expression of a GA catabolic gene (GA2ox) in both PHYA- and PHYB-dependent germination assays [2].
  • Consistent with these gene-expression patterns, the amount of bioactive GA was higher in the pil5 mutant and lower in the PIL5 overexpression line [2].
 

Physical interactions of PIL5

  • PIL5 binds directly to GAI and RGA promoters but not to GA and ABA metabolic gene promoters [3].

References

  1. Cold and light control seed germination through the bHLH transcription factor SPATULA. Penfield, S., Josse, E.M., Kannangara, R., Gilday, A.D., Halliday, K.J., Graham, I.A. Curr. Biol. (2005) [Pubmed]
  2. Light activates the degradation of PIL5 protein to promote seed germination through gibberellin in Arabidopsis. Oh, E., Yamaguchi, S., Kamiya, Y., Bae, G., Chung, W.I., Choi, G. Plant J. (2006) [Pubmed]
  3. PIL5, a phytochrome-interacting bHLH protein, regulates gibberellin responsiveness by binding directly to the GAI and RGA promoters in Arabidopsis seeds. Oh, E., Yamaguchi, S., Hu, J., Yusuke, J., Jung, B., Paik, I., Lee, H.S., Sun, T.P., Kamiya, Y., Choi, G. Plant. Cell (2007) [Pubmed]
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